Evaluation of Plasma Cytokine Levels in Mesobuthus Eupeus (Scorpionida: Buthidae) Scorpion Envenomation in Rats Treated with Polyvalent Antivenom
نویسندگان
چکیده
منابع مشابه
evaluation of plasma cytokine levels in mesobuthus eupeus (scorpionida: buthidae) scorpion envenomation in rats treated with polyvalent antivenom
conclusions our data suggest that using polyvalent antivenom in short time after envenomation could reduce the inflammatory responses related to the systemic changes during the elevation of cytokines in scorpion envenomation. results il-1a, il-6, and tnf-α levels were significantly increased in 3 hours after envenomation in both groups (v and av), but the intensity of increase in av group was l...
متن کاملInhibition of Nephrotoxic Activity of Mesobuthus Eupeus Scorpion Venom by Commercial Polyvalent Antivenom in Rabbits
Background: Immunotherapy is the only specific treatment for scorpion envenomation. In the present study, the protective effects of polyvalent antivenom against histopathological complications in kidneys and marker changes (BUN and creatinine) induced by Mesobuthus eupeus (Me) scorpion venom was investigated in anesthetized rabbits. Methods: Twenty four rabbits were randomized into four gro...
متن کاملPurification of the Immunogenic Fractions and Determination of Toxicity in Mesobuthus eupeus (Scorpionida: Buthidae) Venom
BACKGROUND Scorpions stings are a health problem in many parts of the world. Mesobuthus eupeus (Buthidae) is the most prevalent species in the Middle East and Central Asia. Definition of toxicogenic and immunogenic characteristics of the venom is necessary to produce antidote. In this study, the noted properties of M. eupeus venom were evaluated. METHODS Venom was obtained by milking M. eupeu...
متن کاملNeutralizing effects of polyvalent antivenom on severe inflammatory response induced by Mesobuthus eupeus scorpion venom
This study evaluated the effects of Mesobuthus eupeus (Me) scorpion venom on inflammatory response following injection. Additionally, the present study examined whether immunotherapy at specific time intervals would be effective on inflammatory response after Me venom inoculation. Animals were divided randomly into four groups: the first group received LD50 of venom and the second and third gro...
متن کاملEffects of experimental Mesobuthus eupeus scorpion envenomation on chicken
This study aimed to evaluate the clinical, histopathological and hematological effects of Mesobuthus eupeus venom on chicken organs. Adult chickens were subcutaneously injected with five doses of M. eupeus venom (0.5, 2, 5, 10 and 20 mg/kg; four chickens per each dose). Symptoms were recorded during the experiment and blood samples were collected for hematological analysis. Moreover, a complete...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Jundishapur Journal of Health Sciences
سال: 2015
ISSN: 2252-021X,2252-0627
DOI: 10.5812/jjhs.27159